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. 2016 Jun 28;2016:1232594. doi: 10.1155/2016/1232594

Table 1.

Clinical features of reported gangliocytic paragangliomas in cauda equina region.

Case Age/sex Clinical presentation Location Size (mm) Pathological findings Intervention
Current case 68/M Temporary urinary incontinence, LE, perineal paresthesias S1-S2 intradural 60 × 26 Neuroendocrine cells in Zellballen pattern, ganglion cells, abundant cytoplasm, GFAP (−), S100 (+), synaptophysin (+) Complete surgical resection

Vural et al. [3] 17/M Low back pain, sciatica, difficulty in ambulation L4 intradural 50 × 30 Neuroendocrine cells in Zellballen pattern, ganglion cells, calcification, GFAP (−), S100 (+) Complete surgical resection

Llena et al. [7] 42/M Low back pain, LE weakness L1 intradural 35 × 20 Neuroendocrine cells in Zellballen pattern, large neurons, neurosecretory granules, dopamine (+) Complete surgical resection

Matschke et al. [8] 63/F Low back pain Cauda equina Neuroendocrine cells in Zellballen pattern, vascular tissue, ganglion cells, GFAP (+) Complete surgical resection

Djindjian et al. [9] 36/M Low back pain, sudden paraplegia following sacral infiltration of medication L2–L5 intradural 80 × 30 Cells in Zellballen pattern, large mature neurons, gangliocytic differentiation, neurosecretory granules Complete surgical resection

Mishra et al. [10] described features of 8 paragangliomas in the spinal region, of which two were identified as having prominent gangliocytic differentiation.

Moran et al. [11] described features of 30 different paragangliomas in the spinal region, of which one is classified as gangliocytic.