Table 4.
Hemodynamic parameters, central venous oxygen saturation, dynamic measurement of the liver function (LiMON-System), and lactate before and after the extracorporeal granulocyte therapy (median/0.25–0.75 quartile) measured with the PiCCO-System (under significant reduction of norepinephrine; see Figure 2).
| Before extracorporeal therapy (n = 9) | After extracorporeal therapy (n = 8) | Statistical significance | |
|---|---|---|---|
| CI (L/m2/min) | 3.1 (2.3–3.8) | 3.5 (2.9–3.7) | n.s. |
| SVI (mL/m2) | 42 (33–56) | 45 (40–52) | n.s. |
| MAP (mmHg) | 73 (65–83) | 74 (66–79) | n.s. |
| Heart rate (beat/min) | 73 (67–95) | 76 (70–85) | n.s. |
| SVRI (dyne × sec × cm−5/m2) | 1510 (1150–1730) | 1290 (1130–1760) | n.s. |
| ITBVI (mL/m2) | 1060 (930–1160) | 1000 (960–1120) | n.s. |
| EVLWI (mL/kg) | 7.6 (6.8–9.4) | 7.5 (6.5–8.3) | n.s. |
| cvSpO2 (%) | 73.5 (68.4–76.5) | 71.5 (68.6–79.1) | n.s. |
| Lactate (mmol/L) | 1.5 (1.2–3.0) | 1.3 (1.0–2.7) | n.s. |
| ICG-PDR (%)/ICG-PDR/CI | 13.8 (11.9–15.6.)/4.4 (3.1–5.1) | 14.2 (12.4–17.1)/4.6 (3.1–4.8) | n.s./n.s. |
CI: cardiac index.
cvSpO2: central venous oxygen saturation.
EVLWI: extravascular lung water index.
ICG-PDR: indocyanine green plasma disappearance rate.
ITBVI: intrathoracic blood volume index.
MAP: mean arterial pressure.
n.s.: not (statistically) significant.
SVI: stroke volume index.
SVRI: systemic vascular resistance index.