Table 1.
Patient characteristics of 60 patients with Propionibacterium-associated PJI, presented according to their postoperative antimicrobial treatment
| Characteristic | Rifampicin (n = 39) |
No rifampicin (n = 21) |
Total group (n = 60) |
p-value |
|---|---|---|---|---|
| Location of joint, n | 1.0 | |||
| Knee | 15 | 9 | 24 | |
| Hip | 12 | 6 | 18 | |
| Shoulder | 12 | 6 | 18 | |
| Type of arthroplasty, n | ||||
| Primary/revision | 31/8 | 15/6 | 46/14 | |
| Age at PJI diagnosisa | 69 (40–78) | 69 (47–80) | 69 (40–80) | 0.5 |
| Sex, female/male | 22/17 | 7/14 | 29/31 | 0.09 |
| BMI, kg/m2a | 28 (21–50) | 28 (22–35) | 28 (21–50) | 0.2 |
| Medical history of PJI, n | 2 | 2 | 4 | 0.6 |
| Missing data | 6 | 0 | 6 | |
| Clinical presentation, n | ||||
| Missing data | 1 | 0 | 1 | |
| Joint pain | 31 | 18 | 49 | 1.0 |
| Stiffness | 15 | 10 | 25 | 0.5 |
| Tumor | 9 | 7 | 16 | 0.4 |
| Instability | 7 | 8 | 15 | 0.1 |
| Rubor | 5 | 1 | 6 | 0.4 |
| Sinus tract | 2 | 2 | 4 | 0.6 |
| Calor | 2 | 1 | 3 | 1.0 |
| Fever | 1 | 1 | 2 | 1.0 |
| Wound leakage | 1 | 1 | 2 | 1.0 |
| Laboratory diagnostics | ||||
| ESR > 30 mm/h | 12 | 6 | 18 | 0.5 |
| Missing ESR data | 5 | 3 | 8 | |
| CRP > 10 mg/L | 10 | 6 | 16 | 0.6 |
| Missing CRP data | 8 | 7 | 15 | |
| Leucocytes, × 109/La | 7.9 (5.2–15) | 7.5 (4.9–13) | 7.7 (4.9–15) | 0.6 |
| Missing data, n | 13 | 10 | 23 | |
| Microbiological diagnostics | ||||
| No. of tissue culturesa | 7 (6–9) | 6 (5–10) | 6 (5–10) | 0.3 |
| No. of positive culturesa | 3 (2–9) | 3 (2–7) | 3 (2–9) | 0.8 |
| Mono/polymicrobial | 28/11 | 19/2 | 47/13 | 0.1 |
| PJI classificationb | 0.7 | |||
| Early postoperative | 3 | 1 | 4 | |
| Late chronic | 9 | 4 | 13 | |
| Acute hematogenous | 2 | 0 | 2 | |
| Positive intraoperative cultures | 25 | 16 | 41 |
PJI: periprosthetic joint infection; BMI: body mass index; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein.
a
Values are median (range)
b
According to Tsukayama et al. (1996): early postoperative infection (< 1 month after index surgery), late chronic infection (> 1 month after index surgery), acute hematogenous infection (antecedent bacteremia with acute onset of symptoms in affected joint with the prosthesis), or infection diagnosed from positive intraoperative cultures (≥ 2 positive cultures of the same specimen obtained at the time of revision operation).