Fig. 2.

Genotypic and phenotypic characterisation of P. aeruginosa isolates belonging to the four more frequent PFGE profiles. PFGE dendrograms of the four major clusters (P1, P6, P14, CP2) are reported. Phenotypic traits of adaptation to CF airways and intermittent or chronic status of isolates are indicated. Resistance to at least one member of a specific antibiotic class is indicated as +. * swimming and twitching motility zone diameter, as measured by subsurface stab assay; ° halo diameter; ^# isolates with iridescent and metallic sheen of the colony surface, that is typical for a lasR mutant, are indicated as +; ^§ visible pyocyanin presence +; no visible pyocyanin -; Abbreviations: Isol isolate, Patt PFGE pattern, I/C intermittent or chronic, Muc mucoidy, Twitch twitching motility, Swimm swimming motility, Prot proteases, Sider siderophores, Hyper-mut hyper-mutability (mutation frequency), Pyoc pyocyanin, aminogl aminoglycosides, mono-bact mono-bactams, cephal cephalosporins, fluoroq fluoroquinolones, carbap carbapenems, pen/β-lact inh penicillins/β-lactamase inhibitors, sulfon/folate ant sulfonamides/folate antagonists