Table 3.
Sensitivity, specificity, positive predictive value and negative predictive value of HR-pQCT
| Joints | Total number of breaks on HR-pQCT | Total number of breaks on μCT | Sensitivity | Specificity | Positive predictive value | Negative predictive value |
|---|---|---|---|---|---|---|
| MCP reader 1 | 68 | 79 | 82.1 % | 65 % | 86.8 % | 56.5 % |
| MCP reader 2 | 83 | 156 | 65.6 % | 62.5 % | 87.5 % | 31.3 % |
| PIP reader 1 | 61 | 70 | 81 % | 63.3 % | 75.6 % | 70.4 % |
| PIP reader 2 | 68 | 85 | 75.6 % | 77.4 % | 81.6 % | 70.6 % |
| All reader 1 | 129 | 149 | 81.6 % | 64 % | 81.6 % | 64 % |
| All reader 2 | 151 | 241 | 68.9 % | 69.4 % | 82.6 % | 51.5 % |
Sensitivity, specificity, positive predictive value and negative predictive value of HR-pQCT in the detection of cortical breaks with μCT as gold standard based on the mean score of Reader 1 (readings 1 and 2), and the score of Reader 2
Abbreviations: HR-pQCT high resolution peripheral quantitative computed tomography, μCT microCT