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. 2016 Jul 11;16:449. doi: 10.1186/s12885-016-2506-8

Table 8.

Comparison of inflammatory markers and immunologic factors in two groups with neoadjuvant

Factor and time FTS group (n = 68) Conventional group (n = 70) P value
IL-6 (ng/L)
 Before surgery 50.57 ± 21.45 51.42 ± 19.83 0.979
 POD1 119.54 ± 18.62 131.42 ± 21.58* 0.004
 POD3 138.42 ± 22.73 150.48 ± 21.97* 0.043
 POD7 112.52 ± 19.43 116.43 ± 22.57 0.573
CRP (mg/L)
 Before surgery 4.53 ± 1.24 4.45 ± 1.29 0.942
 POD1 61.32 ± 13.77 70.52 ± 11.56* 0.032
 POD3 132.73 ± 21.56 150.49 ± 25.72* 0.013
 POD7 49.78 ± 15.84 60.43 ± 16.38* 0.035
Globulin (g/l)
 Before surgery 25.67 ± 3.34 25.82 ± 4.39 1.000
 POD1 21.43 ± 3.63 20.21 ± 3.45 0.760
 POD3 24.76 ± 3.82 21.64 ± 2.94* 0.023
 POD7 25.73 ± 3.35 25.87 ± 4.09 0.848
IgG (g/l)
 Before surgery 13.76 ± 3.13 13.62 ± 3.42 0.858
 POD1 7.42 ± 1.42 5.23 ± 1.35* 0.031
 POD3 9.42 ± 3.53 6.44 ± 2.95* 0.001
 POD7 12.56 ± 2.67 11.94 ± 3.83 0.656
IgA (g/l)
 Before surgery 2.19 ± 0.29 2.21 ± 0.25 0.769
 POD1 1.61 ± 0.37 1.34 ± 0.25* 0.017
 POD3 1.85 ± 0.42 1.51 ± 0.51* 0.004
 POD7 2.04 ± 0.37 2.15 ± 0.42 0.753
IgM (g/l)
 Before surgery 1.14 ± 0.31 1.11 ± 0.41 0.893
 POD1 0.71 ± 0.39 0.72 ± 0.33 0.957
 POD3 0.67 ± 0.22 0.64 ± 0.32 0.873
 POD7 1.09 ± 0.43 1.10 ± 0.42 0.673
CD3+
 Before surgery 55.62 ± 2.43 56.82 ± 2.58 0.875
 POD1 46.73 ± 2.52 44.09 ± 2.03* 0.043
 POD3 49.82 ± 2.43 46.17 ± 2.35* 0.033
 POD7 53.85 ± 2.05 54.04 ± 2.73 0.482
CD4+
 Before surgery 42.43 ± 3.57 42.48 ± 4.92 0.803
 POD1 32.52 ± 4.13 29.12 ± 5.02* 0.025
 POD3 35.32 ± 3.90 32.55 ± 5.02* 0.013
 POD7 41.42 ± 5.24 40.98 ± 4.27 0.484
CD4+/CD8+
 Before surgery 1.52 ± 0.41 1.55 ± 0.45 0.842
 POD1 1.33 ± 0.36 1.11 ± 0.41* 0.027
 POD3 1.47 ± 0.56 1.32 ± 0.37* 0.025
 POD7 1.50 ± 0.36 1.52 ± 0.29 0.562

Variables were expressed as the median ± quartile

* P <0.05