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. 2016 Jul 11;16:441. doi: 10.1186/s12885-016-2484-x

Table 6.

Survival under specific treatments

Exon 4 intensity Exon 4 % OPN-c intensity OPN-c %
Logrank Wilcoxon Logrank Wilcoxon Logrank Wilcoxon Logrank Wilcoxon
Treatment n χ2 p-value χ2 p-value χ2 p-value χ2 p-value χ2 p-value χ2 p-value χ2 p-value χ2 p-value
hormone no (all subgroups) 54 7.127 0.008 9.087 0.003 0.106 0.745 0.015 0.902 3.384 0.066 5.373 0.021 0.551 0.458 0.372 0.542
hormone yes (all subgroups) 65 2.631 0.105 6.981 0.008 1.970 0.160 3.267 0.071 0.480 0.489 2.218 0.136 0.130 0.719 0.140 0.708
hormone alone 18 0.591 0.442 0.226 0.635 0.069 0.793 0.071 0.790 1.303 0.254 0.961 0.327 0.050 0.823 0.184 0.668
hormone and chemo 16 2.613 0.106 3.937 0.047 0.531 0.466 1.071 0.301 0.707 0.401 1.778 0.182 0.317 0.573 0.101 0.751
hormone and radiation 10 1.833 0.176 2.709 0.100 0.837 0.360 0.987 0.320 2.049 0.152 2.485 0.115 0.075 0.784 0.011 0.915
hormone, chemo, radiation 21 0.703 0.402 0.601 0.438 1.036 0.309 1.139 0.286 0.065 0.799 0.240 0.624 0.047 0.829 0.089 0.765
chemo no (all subgroups) 30 0.833 0.361 3.472 0.062 0.403 0.526 1.123 0.289 0.067 0.795 0.465 0.495 0.003 0.955 0.049 0.825
chemo yes (all subgroups) 89 6.588 0.010 10.593 0.001 0.387 0.534 0.566 0.452 2.858 0.091 7.465 0.006 0.614 0.433 0.186 0.667
chemo (CMF) 55 5.455 0.020 9.345 0.002 1.275 0.259 1.561 0.212 1.522 0.217 4.847 0.028 0.152 0.697 0.016 0.899
chemo (AC/CMF) 34 1.289 0.256 1.608 0.205 0.420 0.517 0.317 0.574 1.300 0.254 2.740 0.098 0.507 0.477 0.456 0.500
chemo alone 13 1.865 0.172 1.268 0.260 0.107 0.743 0.245 0.620 0.322 0.570 1.356 0.244 0.099 0.753 0.126 0.722
chemo and radiation 39 4.123 0.042 8.229 0.004 0.898 0.344 0.209 0.648 2.380 0.123 3.271 0.071 0.431 0.512 0.180 0.672
radiation no (all subgroups) 47 1.964 0.161 3.638 0.057 0.009 0.927 0.067 0.796 0.005 0.946 0.497 0.481 1.310 0.252 1.819 0.178
radiation yes (all subgroups) 72 3.786 0.052 8.444 0.004 1.143 0.285 1.690 0.194 2.395 0.122 4.766 0.029 0.122 0.727 0.090 0.764

Logrank test and Wilcoxon test for the prediction of survival by the dichotomized immunohistochemical markers in the indicated subgroups of patients. Significant p-values are underlined