Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Antisecretory effects of dihydroxy bile acids in T84 cells
| Bile acid (50 μM) | Hydroxyl group positions | % Control Isc response to CCh (100 μM) |
|---|---|---|
| Deoxycholic acid | 3α‐12α‐OH | 52.5 ± 6.0 (n= 9; P < 0.001) |
| Isodeoxycholic acid | 3β‐12α‐OH | 58.5 ± 7.8 (n= 3; P < 0.05) |
| Lagodeoxycholic acid | 3α‐12β‐OH | 57.5 ± 7.3 (n= 6; P < 0.001) |
| Chenodeoxycholic acid | 3α‐7α‐OH | 51.4 ± 7.4 (n= 6; P < 0.001) |
