Table 4. Adverse events in children who maintained and ceased therapy.
|
Maintained therapy, n (%) |
Ceaseda
therapy, n (%) |
|||
|---|---|---|---|---|
| Parent report | Child report | Parent report | Child report | |
| No | 11/60 (18.3%) | 11/60 (18.3%) | 2/16 (12.5%) | 2/16 (12.5%) |
| Photophobia | 36/60 (60%) | 42/60 (70.0%) | 12/16 (75.0%) | 13/16 (81.2%) |
| Reading problemsb,c | 13/54 (24.1%) | 14/54 (25.9%) | 12/15 (80.0%) | 12/15 (80.0%) |
| Headache | 4/60 (6.7%) | 13/60 (21.7%) | 5/16 (31.2%) | 4/16 (25.0%) |
| Systemic (flushes) | 2/60 (3.3%) | 2/60 (3.3%) | 1/16 (6.2%) | 1/16 (6.2%) |
| Infections (conjunctivitis, blepharitis) | 2/60 (3.3%) | 1/60 (1.7%) | 0/16 (0%) | 0/16 (0%) |
| Other | 6/60 (10.0%) | 4/60 (6.7%) | 2/16 (12.5%) | 3/16 (18.8%) |
a
A total of 16/17 could be included, only 1 participant did not return the questionnaire.
b
Only in children who started to read, n=54 vs n=15.
c
Significant difference (P≤0.01) between those who maintained therapy and those who did not.