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. 2015 Sep 15;75(7):1336–1342. doi: 10.1136/annrheumdis-2015-207760

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Frequency of Clinical Disease Activity Index (CDAI) remission (CDAI <2.8) by tocilizumab (TCZ) treatment. The numbers (n) shown in the legend indicate the number of ongoing treatment courses for which a CDAI value was available within ±30 days of a certain post-baseline time point. At none of the time points was there a significant difference between TCZ treatment types (Fisher's exact tests at 5% level). Treatment groups ‘TCZ’, ‘TCZ+ methotrexate (MTX)’, ‘TCZ+MTX_plus’ and ‘TCZ+other’ represent TCZ as monotherapy and in combination with MTX, MTX+other synthetic disease-modifying antirheumatic drugs (sDMARD(s)) and at least one sDMARD other than MTX, respectively.