Table 2.
Key Sites in the Active Site of Different Gfo/Idh/MocA Proteins
| Protein | Abbreviation | Site1 | Site2 | Site3 | Site4 | Site5 |
|---|---|---|---|---|---|---|
| Catalytic | Catalytic | Nicotinamide bond | ||||
| Aldose‐aldose oxidoreductase | AAOR | K104 | Y189 | D185 | R172 | Y17 |
| α‐N‐Acetylgalactosidase | A‐zyme | (V122) | H228 | Y225 | R213 | R31 |
| 1,5‐anhydro‐D‐fructose reductase | AFR | K94 | H180 | D176 | – | I12 |
| C‐3″‐Ketoreductase | KijD10 | K102 | Y186 | D182 | R170 | I20 |
| Glucose‐fructose oxidoreductase | GFOR | K181 | Y269 | D265 | R252 | Y94 |
| Glucose‐6‐phosphate dehydrogenase | G6PD | K148 | H240 | D235 | – | L17 |
| myo‐inositol dehydrogenase | myo‐IDH | K97 | H176 | (D172) | – | I13 |
| Uridine‐5′‐phosphate‐2,3‐diacetamido‐2,3‐dideoxy‐D‐mannuronic acid dehydrogenase | WlbA | K102 | H188 | N184 | K172 | I13 |