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HLD‐I subfamily tunnels. CAVER was used to identify main and slot tunnels, pink and purple colored, respectively, in HLD‐I subfamily structures: DmrA(4MJ3), DppA(2XT0), DhlA(2DHC), and DppA(5ESR). The Asp123 of the catalytic pentad was used as the center for tunnel calculations. Figure made using PyMOL.25
