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. Author manuscript; available in PMC: 2016 Jul 12.
Published in final edited form as: Int J Obes (Lond). 2010 Nov 2;35(6):785–792. doi: 10.1038/ijo.2010.217

Table 3b.

Associations between changes (delta) in biomarkers in the first 6 months of the weight loss dietary intervention and weight change during the weight loss phase (0–6 months) (model 1) and the weight maintenance/regain phase (7–24 months) (model 2); multivariate regression analysisa

Model 1 to predict weight change between 0–6 months P-value Model 2 to predict weight change between 7–24 months P-value
Leptin, delta 0–6 months 0.505 <0.001 –0.131 0.013
Adiponectin, delta 0–6 months –0.301 0.023 0.111 0.356
CRP, delta 0–6 months 0.028 0.743 0.236 0.002
TG, delta 0–6 months 0.006 0.132 0.003 0.465
HDL-c, delta 0–6 months –0.159 0.001 0.049 0.252
LDL-c, delta 0–6 months 0.029 0.002 0.002 0.838
Fasting glucose, delta 0–6 months 0.001 1.000 –0.016 0.190
Weight change in %, delta 0–6 months –0.102 0.063

Abbreviations: CRP, C-reactive protein; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; TG, triglyceride.

a

Adjusted simultaneously to all the variables in the model + adjusted to the age, sex and diet group. The variables are in continuous form except for sex (men vs women) and diet intervention group (1 = low-fat, 2 = Mediterranean, 3 = low-carbohydrate diet); weight change is measured as percent of changes at 6 months as compared with baseline.