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. Author manuscript; available in PMC: 2016 Jul 12.
Published in final edited form as: Arch Intern Med. 2012 Nov 26;172(21):1644–1650. doi: 10.1001/2013.jamainternmed.85

Table 3. Hazard Ratios for Diabetic and Nondiabetic End-Stage Renal Disease (ESRD) in Adulthood According to Body Mass Index (BMI) Category at Age 17 Yearsa.

Variable Percentile Subgroup
Based on the
2000 CDC Sex-Specific
BMI for Age
Growth Charts
Incident
Cases of
ESRD, No.
Incidence
Rate per 100 000
Person-Years
Crude HR
(95% CI)
Model 1 Adjusted
for Sex, Country
of Origin, and
Period of Enrollment
in the Study,
HR (95% CI)
Model 2 Adjusted
for Sex, Country
of Origin,
Period of Enrollment
in the Study, and
Systolic Blood Pressure,
HR (95% CI)b
Diabetic ESRD (n = 258)
Underweight <5th 4 0.26 0.62 (0.23-1.69) 0.49 (0.18-1.33) 0.49 (0.18-1.34)
Normal weight 5th to 84th 134 0.51 1 [Reference] 1 [Reference] 1 [Reference]
Overweight 85th to 94th 63 2.72 5.39 (3.99-7.27) 6.01 (4.45-8.12) 5.96 (4.41-8.06)
Obese ≥95th 57 8.21 20.58 (15.09-28.06) 19.81 (14.48-27.10) 19.37 (14.13-26.55)

Nondiabetic ESRD (n = 616)
Underweight <5th 31 2.04 1.23 (0.86-1.78) 1.09 (0.76-1.57) 1.09 (0.76-1.57)
Normal weight 5th to 84th 467 1.8 1 [Reference] 1 [Reference] 1 [Reference]
Overweight 85th to 94th 82 3.43 1.99 (1.57-2.51) 2.17 (1.71-2.75) 2.17 (1.71-2.74)
Obese ≥95th 36 5.19 3.35 (2.39-4.71) 3.41 (2.42-4.79) 3.41 (2.42-4.79)

Abbreviations: CDC, US Centers for Disease Control and Prevention; HR, hazard ratio.

a

Normal weight is the reference category for all models. All models yielded P < .001.

b

Systolic blood pressure above or below the 95th age-specific and sex-specific percentiles.