Table 3. Tumor formation of unsorted RCC-41-PDX-2, and sorted RCC-41-PDX-2/CD133+ and RCC-41-PDX-2/CD133− cells in SCID mice as a function of number of injected cells (n = 4 per group).
Number of injected cells per mouse (n = 4) | Number of mice with tumor (Delay 3 weeks) | Number of mice with tumor (Delay 6 weeks) | Number of mice with tumor (Delay 9 weeks) | Number of mice with tumor (Delay 10 weeks) | |
---|---|---|---|---|---|
Unsorted RCC-41-PDX-2 | 102 | 3/4 | 4/4 | - | - |
103 | 4/4 | 4/4 | - | - | |
RCC-41-PDX-2/CD133+ | 102 | 0/4 | 0/4 | 0/4 | 0/4 |
103 | 0/4 | 0/4 | 4/4 | 4/4 | |
RCC-41-PDX-2/CD133− | 102 | 2/4 | 2/4 | 2/4 | 4/4 |
103 | 3/4 | 4/4 | 4/4 | 4/4 |