Figure 3. Effect of clofibrate, fenofibrate, and WY14643 treatment on cytotoxicity.

HMEC, SUM149PT, and SUM1315MO2 cells were untreated or treated with A–C. clofibrate, D–F. fenofibrate, and G–I. WY14643 for differing time points at various concentrations as indicated. Supernatants were collected from untreated and drug treated cells to measure the level of LDH release by spectrophotometer at 490 and 680 nm.