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. 2016 Feb 19;7(13):15828–15839. doi: 10.18632/oncotarget.7489

Table 2. Survival according to RUNX1 expression in the testing group of 157 CN-AML patients.

Outcome All patients, n = 157 ELN Favorable category ELN Intermediate-I category
RUNX1high, n = 78 RUNX1low, n = 79 P RUNX1high, n = 17 RUNX1low, n = 18 P RUNX1high, n = 65 RUNX1low, n = 57 P
OS
Median OS, m 10.46 (0.07–198.7) 37.03 (0.13–214.5) 0.009 58.91 (0.59–169.5) 38.34 (0.3–214.5) 0.65 8.41 (0.07–198.7) 35.91 (0.13–190.3) 0.002
Estimated OS at 3 y. % (95% CI) 0.33 (0.24–0.46) 0.54 (0.45–0.67) 0.01 0.65 (0.46–0.92) 0.56 (0.37–0.84) 0.73 0.25 (0.16–0.38) 0.54 (0.43–0.68) 0.007
EFS
Median EFS, m 7.1 (0.03–198.7) 17.81 (0.03–214.5) 0.011 39.82 (0.03–169.5) 33.03 (0.03–214.5) 0.36 6.57 (0.03–198.7) 15.54 (0.03–190.3) 0.004
Estimated EFS at 3 y. % (95% CI) 0.28 (0.2–0.4) 0.41 (0.31–0.53) 0.005 0.53 (0.34–0.83) 0.56 (0.37–0.84) 0.17 0.2 (0.12–0.33) 0.38 (0.27–0.52) 0.03

CI, confidence interval.