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. 2016 Feb 19;7(13):15828–15839. doi: 10.18632/oncotarget.7489

Table 3. Multivariable analysis with OS and EFS in the testing group of 157 CN-AML patients.

Variable OS, n = 157 EFS, n = 157
HR (95% CI) P HR (95% CI) P
RUNX1 expression, high VS low 1.56 (1.01–2.41) 0.04 1.65 (1.10–2.48) 0.02
Age, per 10-y increase 1.13 (0.98–1.32) 0.09 1.05 (0.92–1.21) 0.47
Sex male VS female 0.82 (0.54–1.23) 0.33 0.99 (0.67–1.46) 0.96
NPM1, mutated VS wild type 0.51 (0.32–0.81) 0.005 0.53 (0.34–0.83) 0.005
FLT3-ITD, mutated VS wild type 1.98 (1.25–3.14) 0.003 1.85 (1.20–2.85) 0.005
CEBPA, mutated VS wild type 0.71 (0.38–1.35) 0.3 0.78 (0.43–1.41) 0.41

HR, hazards ratio; CI, confidence interval.