Table 3. Multivariable analysis with OS and EFS in the testing group of 157 CN-AML patients.
Variable | OS, n = 157 | EFS, n = 157 | ||
---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
RUNX1 expression, high VS low | 1.56 (1.01–2.41) | 0.04 | 1.65 (1.10–2.48) | 0.02 |
Age, per 10-y increase | 1.13 (0.98–1.32) | 0.09 | 1.05 (0.92–1.21) | 0.47 |
Sex male VS female | 0.82 (0.54–1.23) | 0.33 | 0.99 (0.67–1.46) | 0.96 |
NPM1, mutated VS wild type | 0.51 (0.32–0.81) | 0.005 | 0.53 (0.34–0.83) | 0.005 |
FLT3-ITD, mutated VS wild type | 1.98 (1.25–3.14) | 0.003 | 1.85 (1.20–2.85) | 0.005 |
CEBPA, mutated VS wild type | 0.71 (0.38–1.35) | 0.3 | 0.78 (0.43–1.41) | 0.41 |
HR, hazards ratio; CI, confidence interval.