Table 4. miR-486-5p expression and clinicopathologic features in patients with gastric carcinoma.
| Characteristics | miR-486-5p Low/unchanged expression (n=57) | miR-486-5p High expression (n=27) | Significance | |
|---|---|---|---|---|
| χ2 or Fisher's exact test | P-value | |||
| Age(years) | 4.673 | 0.031 | ||
| <60 | 14(24.6) | 13(48.1) | ||
| ≥60 | 43(75.4) | 14(51.9) | ||
| Gender | 1.117 | 0.291 | ||
| Male | 46(80.7) | 19(70.4) | ||
| Female | 11(19.3) | 8(29.6) | ||
| Local invasion | 2.912 | 0.088 | ||
| T1+T2 | 5 (8.8) | 6 (22.2) | ||
| T3+T4 | 52 (91.2) | 21 (77.8) | ||
| Site | 1.625 | 0.202 | ||
| gastric cardia | 13 (22.8) | 3(11.1) | ||
| non-cardia | 44 (77.2) | 24(88.9) | ||
| TNM stage | 0.455 | 0.5 | ||
| I + II | 23 (40.3) | 13 (48.1) | ||
| III + IV | 34 (59.7) | 14 (51.9) | ||
| Nodal status | 2.422 | 0.120 | ||
| positive | 45(78.9) | 17(63.0) | ||
| negative | 12(21.1) | 10(37.0) | ||
| Distant metastasis | 0.591 | |||
| M0 | 55(96.5) | 25(92.6) | ||
| M1 | 2(3.5) | 2(7.4) | ||
| Tumor size (cm) | 1.0 | |||
| ≥10 | 9(15.8) | 4(14.8) | ||
| <10 | 48(84.2) | 23(85.2) | ||
| Depth of tumor invasion Mucosa, submucosa, muscularis propria, subserosa Penetration of serosa, adjacent structures | 40(70.2) | 20(74.1) | 0.712 | |
| 17(29.8) | 7(25.9) | 0.136 | ||