Table 7. Multivariate Cox regression analysis of potential prognostic factors for survival in patients with esophageal squamous cell carcinoma.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR(95%CI) | P-value | HR(95%CI) | P-value | |
| Tumor status, T3-T4 vs. T1-T2 | 7.23(1.76-29.72) | 0.006 | 0.243(0.056-1.049) | 0.058 |
| Stage, III–IV vs. I–II | 2.64(1.51-4.62) | 0.001 | 0.367(0.209-0.644) | 0.000 |
| LNM, yes vs. no | 2.53(1.28-5.02) | 0.008 | 0.472 | |
| Low 486-5p vs. High 486-5p | 2.46(1.35-4.50) | 0.003 | 2.55(1.39- 4.69) | 0.002 |
| Tumor size (cm), ≥10 vs. <10 | 1.97(1.04-3.76) | 0.039 | 0.479(0.247-0.932) | 0.03 |
| Age (years), ≥60 vs.<60 | 1.12(0.64–1.95) | 0.692 | 0.488 | |
| Gender, male vs. female | 1.02(0.55–1.88) | 0.956 | 0.956 | |
| Pathological grade, III vs. I II | 1.48(0.80–2.75) | 0.212 | 0.621 | |