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. 2016 Feb 16;7(13):15885–15900. doi: 10.18632/oncotarget.7419

Figure 3.

Figure 3

A. Network based on the direct interactions among five herbs (Radix Aconiti, Herba Ephedrae, Radix Astragali, Radix Glycytthizae and Raidix Paeoniae Alba), putative targets of WTD and known RA-related targets (herbs-putative targets-known RA targets network). Circular nodes refer to the putative targets of WTD; Triangle nodes refer to the known RA-related targets; Nodes with red highlights refer to the overlap between the putative targets of WTD and known RA-related targets; The size of the nodes were ordered according to their degree in the network. B. Network based on the direct interactions among the five herbs (Radix Aconiti, Herba Ephedrae, Radix Astragali, Radix Glycytthizae and Raidix Paeoniae Alba), major nodes of herbs-putative targets-known RA targets network and their associated pathways (herbs-major putative targets-pathway network). Nodes with yellow highlights refer to the major components involved into the corresponding pathways.