Table 3. Multivariate Cox regression for CSS in MTC patients from SEER database.
| Independent variable | Multivariate Analysis | |
|---|---|---|
| HR (95% CI) | P value | |
| Sex (Female vs. Male) | 1.238 (0.770–1.990) | 0.379 |
| Age (years) | ||
| ≤ 49 | 1 (Reference) | |
| 50-69 | 2.853 (1.631–4.992) | 0.001 |
| ≥ 70 | 5.804 (2.915–11.555) | 0.001 |
| Race (White vs. Black) | 0.344 (0.188–0.630) | 0.001 |
| T stage (T3/4 vs. T1/2) | 3.931 (2.093–7.381) | 0.001 |
| N stage | ||
| N0 | 1 (Reference) | |
| N1a | 3.269 (1.386–7.710) | 0.007 |
| N1b | 3.991 (1.548–10.292) | 0.004 |
| Distant metastasis | 3.998 (2.419–6.606) | 0.001 |
Abbreviations: MTC, medullary thyroid cancer; CSS, cancer-specific survival; SEER, Surveillance, Epidemiology, and End Results; HR, hazard ratio; CI, confidence interval.