Figure 7. Development of metastatic prostate cancer in PTEN/P53-DKO mice.
A. Comparison of metastatic prostate cancer development in conditional PTEN and PTEN/P53 knockout mice. B. Representative images of distant metastasis in PTEN/P53-DKO mice. C. Histological and IHC staining of phosphorylated AKT and AR prostate cancer metastasis growing in lung.