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A., Comparison of individual outcomes for PTEN/P53-DKO mice randomized to control or AZD5363 (M0, no metastasis present; M1, metastasis present; PS (+), favorable performance status; PS (−), poor performance status). Kaplan-Meier plots of overall survival for PTEN/P53-DKO control and AZD5363 treated versus the presence of metastasis B. and performance status C..
