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. 2016 Feb 21;7(13):16012–16022. doi: 10.18632/oncotarget.7559

Figure 3. 20 lncRNAs were shared by our analyses and LCALs.

Figure 3

A. Expression heatmap of the 20 lncRNAs in the GSE27262 dataset B. High expression level of LCAL6 indicates poor prognosis of LUAD patients (C, HR = 1.945, 95% CI: 1.081-3.501, P = 0.027,). In an expression cohort of NSCLC patients, LCAL6 level was higher D. in LUAD compared with LSCC and higher in patients with larger tumor size E. CCK8 assay (F, A549 cells; G, H1299 cells) and EdU (H, A549 cell) assay showed that silence of LCAL6 by siRNA inhibited LUAD cells proliferation. In the xenograft tumor models, silence of LCAL6 inhibited xenograft tumor growth in vivo (I);J, tumor volume; K: tumor weight.