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. 2016 Feb 23;7(13):16248–16261. doi: 10.18632/oncotarget.7637

Table 2. Univariate and multivariate analysis of overall survival in HCC patients.

Variables Univariate analysis Multivariate analysis
HR 95% CI p value HR 95% CI P value
Age 0.945 0.611-1.463 0.801
Gender 0.899 0.534-1.515 0.690
HBsAg 1.161 0.599-2.250 0.658
Tumor size 1.590 1.032-2.450 0.035* 1.152 0.706-1.880 0.572
Tumor number 2.439 1.442-4.126 0.001* 1.598 0.874-2.920 0.128
Tumor encapsulation 1.278 0.980-1.665 0.070
TNM stage 1.845 1.398-2.435 <0.001* 1.419 0.995-2.024 0.054
Liver cirrhosis 0.919 0.539-1.569 0.758
Histological differeniation 0.979 0.722-1.328 0.891
AFP 1.131 0.732-1.745 0.579
BRD7 2.766 1.713-4.465 <0.001* 2.289 1.396-3.753 0.001*

HR, hazard ratio; CI, confidence interval; HBsAg, Hepatitis B surface antigen; AFP, alpha-fetoprotein.

*

Statistically significant (P < 0.05).