Table 2. Univariate and multivariate analysis of overall survival in HCC patients.
Variables | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | P value | |
Age | 0.945 | 0.611-1.463 | 0.801 | |||
Gender | 0.899 | 0.534-1.515 | 0.690 | |||
HBsAg | 1.161 | 0.599-2.250 | 0.658 | |||
Tumor size | 1.590 | 1.032-2.450 | 0.035* | 1.152 | 0.706-1.880 | 0.572 |
Tumor number | 2.439 | 1.442-4.126 | 0.001* | 1.598 | 0.874-2.920 | 0.128 |
Tumor encapsulation | 1.278 | 0.980-1.665 | 0.070 | |||
TNM stage | 1.845 | 1.398-2.435 | <0.001* | 1.419 | 0.995-2.024 | 0.054 |
Liver cirrhosis | 0.919 | 0.539-1.569 | 0.758 | |||
Histological differeniation | 0.979 | 0.722-1.328 | 0.891 | |||
AFP | 1.131 | 0.732-1.745 | 0.579 | |||
BRD7 | 2.766 | 1.713-4.465 | <0.001* | 2.289 | 1.396-3.753 | 0.001* |
HR, hazard ratio; CI, confidence interval; HBsAg, Hepatitis B surface antigen; AFP, alpha-fetoprotein.
Statistically significant (P < 0.05).