Table 3. Univariate and multivariate analysis of recurrence-free survival in HCC patients.
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p value | HR | 95% CI | P value | |
| Age | 1.256 | 0.834-1893 | 0.275 | |||
| Gender | 0.768 | 0.468-1.262 | 0.298 | |||
| HBsAg | 1.590 | 0.798-3.168 | 0.187 | |||
| Tumor size | 1.695 | 1.122-2.561 | 0.012* | 1.136 | 0.698-1.850 | 0.608 |
| Tumor number | 2.770 | 1.663-4.613 | <0.001* | 2.207 | 1.230-3.960 | 0.008* |
| Tumor encapsulation | 1.354 | 1.046-1.753 | 0.021* | 1.252 | 0.961-1.630 | 0.095 |
| TNM stage | 1.817 | 1.387-2.381 | <0.001* | 1.425 | 0.999-2.033 | 0.051 |
| Liver cirrhosis | 1.030 | 0.608-1.744 | 0.914 | |||
| Histological differeniation | 1.159 | 0.868-1.546 | 0.317 | |||
| AFP | 1.540 | 1.022-2.321 | 0.039* | 1.618 | 1.056-2.478 | 0.027* |
| BRD7 | 1.934 | 1.259-2.973 | 0.003* | 1.480 | 0.942-2.326 | 0.089 |
HR, hazard ratio; CI, confidence interval; HBsAg, Hepatitis B surface antigen; AFP, alpha-fetoprotein.
*
Statistically significant (P < 0.05).