Table 1. Frequency of IDH1-R132H and ATRX loss in gliomas.
Histology | IDH | ATRX | IDH_R132H+ATRX_loss | ||||||
---|---|---|---|---|---|---|---|---|---|
total | R132H | frequency | total | loss | frequency | R132H | loss | frequency | |
A | 64 | 37 | 57.81 | 64 | 49 | 76.56 | 37 | 34 | 91.89 |
AA | 27 | 13 | 48.15 | 27 | 21 | 77.78 | 13 | 10 | 76.92 |
O | 12 | 9 | 75.00 | 12 | 1 | 8.33 | 9 | 1 | 11.11 |
AO | 9 | 5 | 55.56 | 9 | 1 | 11.11 | 5 | 1 | 20.00 |
OA | 49 | 40 | 81.63 | 49 | 23 | 46.94 | 40 | 21 | 52.50 |
AOA | 68 | 38 | 55.88 | 68 | 20 | 29.41 | 38 | 15 | 39.47 |
pGBM | 114 | 17 | 14.91 | 114 | 14 | 12.28 | 17 | 5 | 29.41 |
sGBM | 59 | 40 | 67.80 | 59 | 45 | 76.27 | 40 | 36 | 90.00 |
Abbreviations: A, astrocytoma; AA, anaplastic astrocytoma; O, oligodendroglioma; AO, anaplastic oligodendroglioma; OA, oligoastrocytoma; AOA, anaplastic oligoastrocytoma; pGBM, primary glioblastoma; sGBM, secondary glioblastoma; IDH, isocitrate dehydrogenase, ATRX, alpha-thalassemia/mental retardation, X-linked.