Table 3. Cox regression analysis for the progression-free survival of patients with gliomas.

	Univariate Cox Model			Mutivariate Cox Model
	Hazard ratio	95%CI	p value	Hazard ratio	95%CI	p value
Age ≤ 45 vs. > 45	0.703	0.523–0.946	0.02	0.89	0.509–1.03	0.474
Male vs. Female	0.906	0.686–1.197	0.488
Astrocytic vs. oligodendroglial	1.123	0.849–1.486	0.417
IDH1-R132H positive vs. negative	0.437	0.326–0.586	3.15E–08	0.517	0.369–0.723	1.19E–04
ATRX loss vs. expression	0.645	0.486–0.856	0.002	0.913	0.659–1.264	0.584
WHO grade II/III vs. IV	0.529	0.388–0.772	5.79E–05	0.724	0.509–1.030	0.072

Abbreviations: WHO, World Health Organization; PFS, progression-free survival; LGG, low grade glioma; pA, primary astrocytoma; pO, primary oligodendroglioma; pOA, primary oligoastrocytoma; AG, anaplastic glioma; pAA, primary anaplastic astrocytoma; pAO, primary anaplastic oligodendroglioma; pAOA, primary anaplastic oligoastrocytoma; pGBM, primary glioblastoma; IDH, isocitrate dehydrogenase, ATRX, alpha-thalassemia/mental retardation, X-linked.