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. 2016 Feb 19;7(13):16445–16461. doi: 10.18632/oncotarget.7501

Figure 3. mAb04-MICA inhibited the proliferation, invasion and tube formation of HUVECs.

Figure 3

A. mAb04-MICA (Data were presented as the mean ± SD, n = 5, *p < 0.05, **p < 0.01)/mAb04 (n = 5, #p < 0.05, ##p < 0.01) inhibited the proliferation of HUVECs with VEGF stimulated in dose-dependent manner. B, C. Photomicrographs and quantative analysis of transwell invasion assay indicated that mAb-04 suppressed the invasion of HUVECs in dose-dependent manner. D, E. HUVECs tube-like photomicrographs and quantitative analysis demonstrated the significant effects of mAb04-MICA/mAb04 on HUVECs tube formation (Data were presented as the mean ± SD, n = 5 (C, E), *p < 0.05, **p < 0.01, NS, no significance).