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. 2016 Feb 24;7(13):16479–16489. doi: 10.18632/oncotarget.7660

Figure 3. Cytotoxicity of CVV towards CPT11-resistant cells may overcome the stem cell-like cancer cell population.

Figure 3

(A) The percent viability of 4 different colorectal cancer cells (CRCs) shows their resistance to CPT11 exposure, but not to CVV infection. (B) The percentage of the CD133+/CD44+ double-positive cell population, which represents SCCs, with CD133+ and CD44+ cells (left panel) and the percent viability of each CRC following CVV infection (MOI = 10) and CPT11 treatment (10 μM) (right panel). The relative expression of ABCG2 (bottom panel) shows its relationship to drug resistance and the SCC population.