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. 2016 Feb 24;7(13):16529–16541. doi: 10.18632/oncotarget.7664

Table 2. Correlation between AQP3, CD44 expression and clinicopathological features in GC.

Clinicopathological features n AQP3 CD44
+ P-value + P-value
Age 0.817 0.194
 < 60 33 24 7 17 16
 ≥ 60 47 39 10 31 16
Sex 0.305 0.261
 Male 58 44 14 37 21
 Female 22 19 3 11 11
Lauren classification 0.034 0.002
 Intestinal 48 34 14 22 26
 Diffuse and mixed 32 29 3 26 6
Tumor size 0.389 0.242
 ≥ 3 54 44 10 30 24
 < 3 26 19 7 18 8
Tumor location 0.604 0.818
 Upper third 28 21 7 17 11
 Middle third 20 15 5 13 7
 lower third 32 27 5 18 14
Depth of tumor invasion 0.879 0.923
 Localized in subserosa 27 21 6 16 11
 Beyond subserosa 53 42 11 32 21
Lymph node metastasis 0.006 0.049
 N0 25 15 10 11 14
 N1- N3 55 48 7 37 18
pTNM stage 0.584 0.404
 I/II 33 25 8 18 15
 III/IV 47 38 9 30 17
Lymphovascular invasion 0.024 0.044
 Absence 52 37 15 27 25
 Presence 28 26 2 21 7