Table 2. Correlation between AQP3, CD44 expression and clinicopathological features in GC.
Clinicopathological features | n | AQP3 | CD44 | ||||
---|---|---|---|---|---|---|---|
+ | – | P-value | + | – | P-value | ||
Age | 0.817 | 0.194 | |||||
< 60 | 33 | 24 | 7 | 17 | 16 | ||
≥ 60 | 47 | 39 | 10 | 31 | 16 | ||
Sex | 0.305 | 0.261 | |||||
Male | 58 | 44 | 14 | 37 | 21 | ||
Female | 22 | 19 | 3 | 11 | 11 | ||
Lauren classification | 0.034 | 0.002 | |||||
Intestinal | 48 | 34 | 14 | 22 | 26 | ||
Diffuse and mixed | 32 | 29 | 3 | 26 | 6 | ||
Tumor size | 0.389 | 0.242 | |||||
≥ 3 | 54 | 44 | 10 | 30 | 24 | ||
< 3 | 26 | 19 | 7 | 18 | 8 | ||
Tumor location | 0.604 | 0.818 | |||||
Upper third | 28 | 21 | 7 | 17 | 11 | ||
Middle third | 20 | 15 | 5 | 13 | 7 | ||
lower third | 32 | 27 | 5 | 18 | 14 | ||
Depth of tumor invasion | 0.879 | 0.923 | |||||
Localized in subserosa | 27 | 21 | 6 | 16 | 11 | ||
Beyond subserosa | 53 | 42 | 11 | 32 | 21 | ||
Lymph node metastasis | 0.006 | 0.049 | |||||
N0 | 25 | 15 | 10 | 11 | 14 | ||
N1- N3 | 55 | 48 | 7 | 37 | 18 | ||
pTNM stage | 0.584 | 0.404 | |||||
I/II | 33 | 25 | 8 | 18 | 15 | ||
III/IV | 47 | 38 | 9 | 30 | 17 | ||
Lymphovascular invasion | 0.024 | 0.044 | |||||
Absence | 52 | 37 | 15 | 27 | 25 | ||
Presence | 28 | 26 | 2 | 21 | 7 |