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. 2016 Feb 24;7(13):16581–16592. doi: 10.18632/oncotarget.7667

Figure 6. Selinexor acts independently of p53 in LPS (LPS510 and p53 knocked-down LP6).

Figure 6

(A) Cell cycle analysis by propidium iodide staining in the p53-mutant LPS510 line. The cells were fixed following 24-hour exposure of each drug. (B) Cell cycle analysis by propidium iodide staining in the LP6 lines that were treated with control or p53 siRNA. The cells were fixed following 24-hour exposure of each drug. (C) Protein expression analysis in the p53-mutant LPS510 line following 24-hour exposure of each drug. (D) Protein expression analysis in the LP6 lines transfected with control or p53 siRNA following 24-hour exposure of each drug. (E) Cell viability assay in the p53-knocked down LP6 lines following the 72-hour exposure to the serial concentration of selinexor.