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. 2016 Feb 27;7(13):16745–16759. doi: 10.18632/oncotarget.7778

Table 1. Expression of Slug, NOR, and FOXA1 proteins in NPC samples and their association with clinicopathological data of NPC patients.

Slug(+/−) NOR1(+/−) FOXA1 (+/−)
Histological types
NPE (n = 5)a 0/5 5/0 5/0
Ad-NPE (n = 26)b 7/19 25/1 11/15
NPC (n = 33)c 25/8 2/31 5/28
Pac 0.001* 0.000* 0.000*
Pbc 0.000* 0.000* 0.020*
Clinical Stage
I - II (n = 11) 6/5 0/11 3/8
III-IV (n = 22) 19/3 2/20 2/20
P 0.044* 0.302 0.170
lymph node metastasis
YES (n = 19) 15/4 2/17 1/18
NO (n = 14) 10/4 0/14 4/10
P 0.618 0.210 0.065
Age
< 50 (n = 20) 17/3 2/18 2/18
≥ 50 (n = 13) 8/5 0/13 3/10
P 0.124 0.239 0.306
Gender
Female (n = 6) 6/0 0/6 2/4
Male (n = 27) 19/8 2/25 3/24
P 0.126 0.492 0.170

NPE: Inflammatory nasopharyngeal epithelium

Ad-NPE: non-cancerous nasopharyngeal epithelium adjacent to NPC

NPC: nasopharyngeal carcinoma

(+), immunostaining positive. (−), immunostaining negative