Table 1. Expression of Slug, NOR, and FOXA1 proteins in NPC samples and their association with clinicopathological data of NPC patients.
| Slug(+/−) | NOR1(+/−) | FOXA1 (+/−) | |
|---|---|---|---|
| Histological types | |||
| NPE (n = 5)a | 0/5 | 5/0 | 5/0 |
| Ad-NPE (n = 26)b | 7/19 | 25/1 | 11/15 |
| NPC (n = 33)c | 25/8 | 2/31 | 5/28 |
| Pac | 0.001* | 0.000* | 0.000* |
| Pbc | 0.000* | 0.000* | 0.020* |
| Clinical Stage | |||
| I - II (n = 11) | 6/5 | 0/11 | 3/8 |
| III-IV (n = 22) | 19/3 | 2/20 | 2/20 |
| P | 0.044* | 0.302 | 0.170 |
| lymph node metastasis | |||
| YES (n = 19) | 15/4 | 2/17 | 1/18 |
| NO (n = 14) | 10/4 | 0/14 | 4/10 |
| P | 0.618 | 0.210 | 0.065 |
| Age | |||
| < 50 (n = 20) | 17/3 | 2/18 | 2/18 |
| ≥ 50 (n = 13) | 8/5 | 0/13 | 3/10 |
| P | 0.124 | 0.239 | 0.306 |
| Gender | |||
| Female (n = 6) | 6/0 | 0/6 | 2/4 |
| Male (n = 27) | 19/8 | 2/25 | 3/24 |
| P | 0.126 | 0.492 | 0.170 |
NPE: Inflammatory nasopharyngeal epithelium
Ad-NPE: non-cancerous nasopharyngeal epithelium adjacent to NPC
NPC: nasopharyngeal carcinoma
(+), immunostaining positive. (−), immunostaining negative