Figure 4. After siMMP-13 knockdown, the wound-healing migration ability was downregulated in the oral cancer cells.

Mock and MMP-13 knockdown cells were seeded in a 12-well dish overnight. A wound was created at 0 h. (A) Photographs of the wound at 0, 8, 16, and 24 h. (B) Size of the healing area, which was calculated using Axio Vision 4. Error bars denote the mean ± SEM (n = 3). *P < .05 and **P < .01.