Skip to main content
. 2016 Mar 6;7(13):17144–17161. doi: 10.18632/oncotarget.7942

Figure 8. Downregulation in the G1 phase was induced by shMMP-13 transfection in oral cancer cells.

Figure 8

MMP-13-silenced OC3 and OC3-I5 cells were incubated with PI for 15 min. Subsequently, the cells were analyzed through flow cytometry, and the DNA content was quantified. (A) Cell count is represented on the Y axis, and PI is represented on the X axis. Cell cycle status was analyzed according to the DNA content, and the Gl, S, and G2/M phases were calculated. The G1 phase was downregulated, and S and G2/M phases were upregulated after shMMP-13 knockdown. The G1 and G2/M phases were downregulated, and the S phase was upregulated after MMP-13 overexpression. (B) The percentage of the cell cycle status was quantified. Error bars denote the mean ± SEM (n = 3). *P < .05 and **P < .01.