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. 2016 Feb 26;7(13):17162–17181. doi: 10.18632/oncotarget.7751

Figure 8. PLK1 siRNA mimics ER maleate effect on inhibition of cell viability, and PLK1 and Syk partially rescue ER maleate-reduced cell viability.

Figure 8

A, B. PLK1 siRNA transfection decreased cell viability in SCC4 (A) and Cal33 cells (B). Inset: siRNA mediated knockdown of PLK1 expression was shown in both cells by western blot (A, B). β-actin served as a loading control. C–F. Overexpression of PLK1 and Syk increased cell viability in a dose dependent manner in SCC4 (C, E) and Cal33 cells (D-F) and partially rescued ER maleate (1 μM) reduced cell viability both cells (C-F). The bar graph data were presented as mean ± SEM; groups denoted by different letters represent a significant difference at p < 0.05 (ANOVA followed by Fisher's LSD test).