Table 4. Risk of developing non-cardia gastric cancer by chronic atrophic gastritis, H. pylori infection and CagA seropositivity.

Chronic atrophic gastritis	H. pylori infection	Sample (n)	Cases (n)	Crude incidence rate†	HR (95% CI)‡
Any	IgG−/CagA−, or IgG+/CagA−	6,883	4	5.50	Ref
Any	IgG+/CagA+	2,608	17	62.09	18.06 (2.42–134.92)
None	Any	8,828	15	16.13	Ref
Present	Any	663	6	84.73	4.77 (1.82–12.49)
None	IgG−/CagA−, or IgG+/CagA−	6,535	3	4.35	Ref
Present	IgG−/CagA−, or IgG+/CagA−	348	1	26.49	5.55 (0.57–53.97)
None	IgG+/CagA+	2,293	12	49.85	11.21 (3.16–39.84)
Present	IgG+/CagA+	315	5	151.20	32.39 (7.63–137.62)

Abbreviations: CagA, cytotoxin-associated gene A; CI, confidence interval; H. pylori, Helicobacter pylori; HR, hazard ratio.

^†Per 100,000 person-years

^‡Adjusted for age, sex, education level, smoking status and alcohol consumption.