Table 2. Cell line characteristics and their mutational status.
Cell line | Type | Important mutations and deletions |
---|---|---|
8505c | ATC | BRAFV600E/−, P53 mutation |
BCPAP | PTC | BRAFV600E/WT, P53 mutation |
SW1736 | ATC | BRAFV600E/WT, P53 mutation |
TPC-1 | PTC | BRAFWT, RET/PTC, PIK3A |
HTh-7 | ATC | BRAFWT, PTEN−/−, NRAS |
HTORi | NT | BRAFWT |
A375 | MEL | BRAFV600E/WT, P53 mutation |
A2058 | MEL | BRAFV600E/WT, PTEN−/−, P53 mutation |
MEL-JUSO | MEL | BRAFWT, RET/PTC, NRAS |
UACC-903 | MEL | BRAFV600E/WT, PTEN mutation |
NT - Normal thyroid, MEL - Melanoma, ATC – Anaplastic Thyroid Cancer, PTC - Papillary Thyroid Cancer.