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. 2016 Feb 19;7(13):17265–17274. doi: 10.18632/oncotarget.7504

Table 2. Distributions of KRAS mutations in the selected patients.

Clinical characteristic n KRAS mutation (n%) Univariate OR (95%CI) Multivariate OR (95%CI)
Total 495 143(28.9%)
gender
women 184 50(27.1%) 1(reference) 1(reference)
men 311 93(29.9%) 1.1(0.8-1.7) 1.2(0.8-1.8)
age
≤53 137 27(19.7%) 1(reference) 1(reference)
54-60 124 36(29.0%) 1.7(1.0-3.0) 1.6(0.9-3.0)
61-66 119 46(38.6%) 2.6(1.5-4.5) 2.3(1.3-4.1)
>66 115 33(28.6%) 1.6(0.9-2.9) 1.5(0.8-2.7)
location
Right colon 149 46(30.9%) 1(reference) 1(reference)
Left colon 346 97(28.0%) 0.9(0.6-1.3) 0.9(0.5-1.4)
histology
TA 155 24(15.5%) 1(reference) 1(reference)
TVA 123 46(37.4%) 3.3(1.8-5.8) 3.0(1.7-5.4)
SA 52 12(23.1%) 1.6(0.8-3.6) 1.5(0.7-3.2)
VA 7 3(43.0%) 4.1(0.9-19.4) 3.8(0.8-18.4)
HPs 65 20(30.8%) 2.4(1.2-4.8) 2.3(1.2-4.6)
HGIN 93 38(40.9%) 3.8(2.1-6.9) 3.5(1.9-6.5)

TA= Tubular adenoma, TVA= Tubulovillous adenoma, SA= Serrated adenoma, VA= Villous adenoma, HPs= Hyperplastic polyps, HGIN= High grade intraepithelial neoplasia