Table 2. Distributions of KRAS mutations in the selected patients.
Clinical characteristic | n | KRAS mutation (n%) | Univariate OR (95%CI) | Multivariate OR (95%CI) |
---|---|---|---|---|
Total | 495 | 143(28.9%) | ||
gender | ||||
women | 184 | 50(27.1%) | 1(reference) | 1(reference) |
men | 311 | 93(29.9%) | 1.1(0.8-1.7) | 1.2(0.8-1.8) |
age | ||||
≤53 | 137 | 27(19.7%) | 1(reference) | 1(reference) |
54-60 | 124 | 36(29.0%) | 1.7(1.0-3.0) | 1.6(0.9-3.0) |
61-66 | 119 | 46(38.6%) | 2.6(1.5-4.5) | 2.3(1.3-4.1) |
>66 | 115 | 33(28.6%) | 1.6(0.9-2.9) | 1.5(0.8-2.7) |
location | ||||
Right colon | 149 | 46(30.9%) | 1(reference) | 1(reference) |
Left colon | 346 | 97(28.0%) | 0.9(0.6-1.3) | 0.9(0.5-1.4) |
histology | ||||
TA | 155 | 24(15.5%) | 1(reference) | 1(reference) |
TVA | 123 | 46(37.4%) | 3.3(1.8-5.8) | 3.0(1.7-5.4) |
SA | 52 | 12(23.1%) | 1.6(0.8-3.6) | 1.5(0.7-3.2) |
VA | 7 | 3(43.0%) | 4.1(0.9-19.4) | 3.8(0.8-18.4) |
HPs | 65 | 20(30.8%) | 2.4(1.2-4.8) | 2.3(1.2-4.6) |
HGIN | 93 | 38(40.9%) | 3.8(2.1-6.9) | 3.5(1.9-6.5) |
TA= Tubular adenoma, TVA= Tubulovillous adenoma, SA= Serrated adenoma, VA= Villous adenoma, HPs= Hyperplastic polyps, HGIN= High grade intraepithelial neoplasia