Table 3. Distributions of different type mutations of KRAS.
| Codon12(AA) | Codon13(AA) | Mutation type | n% |
|---|---|---|---|
| Single mutations | |||
| GAT(Asp) | transition | 62(43.4%) | |
| GTT(Val) | transversion | 27(18.9% | |
| TGT(Cys) | transversion | 8(5.6%) | |
| GCT (Ala) | transversion | 4(2.8%) | |
| GAC (Asp) | transition | 28(19.6%) | |
| TGC (Cys) | transversion | 1(0.7%) | |
| AGC (13Ser) | transversion | 1(0.7%) | |
| Double mutations | |||
| GAT(Asp) | GAC (Asp) | Transition | 6(4.2%) |
| GAT;GTT(Asp; Val) | Transition/transversion | 3(2.1%) | |
| AGT ;GCT(Ser;Ala) | transversion | 1(0.7%) | |
| GAT;GCT(Asp; Ala) | Transition/transversion | 1(0.7%) | |
| GAT(Asp) | TGC (Cys) | Transition/transversion | 1(0.7%) |
AA=amino acids