Table 4. Distributions of BRAF mutations in the selected patients.
Clinical characteristic | n | BRAF mutation (n%) | Univariate OR (95%CI) | Multivariate OR (95%CI) |
---|---|---|---|---|
Total | 495 | 143(28.9%) | ||
sex | ||||
women | 184 | 32(17.4%) | 1(reference) | 1(reference) |
men | 311 | 45(14.4%) | 0.8(0.5-1.3) | 0.7(0.4-1.2) |
age | ||||
≤53 | 137 | 15(10.9%) | 1(reference) | 1(reference) |
54-60 | 124 | 24(19.4%) | 1.4(0.7-2.8) | 1.8(0.8-4.0) |
61-66 | 119 | 21(17.6%) | 1.4(0.7-2.8) | 1.3(0.6-3.0) |
>66 | 115 | 17(14.8%) | 1.1(0.5-2.1) | 1.0(0.4-2.2) |
location | ||||
Right colon | 149 | 18(12.1%) | 1(reference) | 1(reference) |
Left colon | 346 | 59(17.1%) | 1.5(0.85-2.6) | 1.6(0.9-2.7) |
histology | ||||
TA | 155 | 8(5.2%) | 1(reference) | 1(reference) |
TVA | 123 | 10(8.1%) | 1.5(0.6-4.3) | 1.8(0.7-4.7) |
SA | 52 | 26(50.0%) | 18.4(7.5-45) | 20.6(8.2-51.8) |
VA | 7 | 4(57.0%) | 24.5(4.7-128.5) | 26.2(4.7-144.2) |
HPs | 65 | 24(36.9%) | 10.8(4.5-25.7) | 11.9(4.9-29.0) |
HGIN | 93 | 5(5.3%) | 1.0(0.3-3.3) | 1.1(0.3-3.5) |
TA= Tubular adenoma, TVA= Tubulovillous adenoma, SA= Serrated adenoma, VA= Villous adenoma, HPs= Hyperplastic polyps, HGIN= High grade intraepithelial neoplasia