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. 2016 Feb 19;7(13):17265–17274. doi: 10.18632/oncotarget.7504

Table 4. Distributions of BRAF mutations in the selected patients.

Clinical characteristic n BRAF mutation (n%) Univariate OR (95%CI) Multivariate OR (95%CI)
Total 495 143(28.9%)
sex
women 184 32(17.4%) 1(reference) 1(reference)
men 311 45(14.4%) 0.8(0.5-1.3) 0.7(0.4-1.2)
age
≤53 137 15(10.9%) 1(reference) 1(reference)
54-60 124 24(19.4%) 1.4(0.7-2.8) 1.8(0.8-4.0)
61-66 119 21(17.6%) 1.4(0.7-2.8) 1.3(0.6-3.0)
>66 115 17(14.8%) 1.1(0.5-2.1) 1.0(0.4-2.2)
location
Right colon 149 18(12.1%) 1(reference) 1(reference)
Left colon 346 59(17.1%) 1.5(0.85-2.6) 1.6(0.9-2.7)
histology
TA 155 8(5.2%) 1(reference) 1(reference)
TVA 123 10(8.1%) 1.5(0.6-4.3) 1.8(0.7-4.7)
SA 52 26(50.0%) 18.4(7.5-45) 20.6(8.2-51.8)
VA 7 4(57.0%) 24.5(4.7-128.5) 26.2(4.7-144.2)
HPs 65 24(36.9%) 10.8(4.5-25.7) 11.9(4.9-29.0)
HGIN 93 5(5.3%) 1.0(0.3-3.3) 1.1(0.3-3.5)

TA= Tubular adenoma, TVA= Tubulovillous adenoma, SA= Serrated adenoma, VA= Villous adenoma, HPs= Hyperplastic polyps, HGIN= High grade intraepithelial neoplasia