Table 6. Clinical features in death of rheumatoid arthritis patients with nontuberculous mycobacteria (NTM) infections.
Variables* | n | % |
---|---|---|
Age at entry, (years) | ||
mean ± SD | 73.3 ± 17.5 | |
NTM infection in RA duration (years) | 7.0 ± 4.3 | |
BMI†, kg/m2 | 21.3 ± 3.6 | |
year | ||
18–44 | 1 | 12.5 |
45–64 | 1 | 12.5 |
≥65 | 6 | 75.0 |
Gender | ||
Male | 5 | 62.5 |
TB history | 4 | 50.0 |
Biologics used | 1† | 12.5 |
Comorbidity | ||
Hypertension | 5 | 62.5 |
Cancer | 3 | 37.5 |
COPD | 2 | 25.0 |
CKD | 2 | 25.0 |
Diabetes mellitus | 1 | 12.5 |
NTM invasive site | ||
pulmonary | 6 | 75.0 |
extrapulmonary | 2 | 25.0 |
Antimicrobial therapy | 5 | 62.5 |
EMB+RIF | 2 | |
Clarithromycin | 2 | |
EMB+Ciprofloxacin | 1 | |
The average time of death after NTM infection (years) | ||
mean ± SD | 1.12 ± 0.87 | |
NTM species | ||
M. intracellulare | 5 | 62.5 |
M. chelonae | 1 | 12.5 |
M. peregrinum | 1 | 12.5 |
M. terrae | 1 | 12.5 |
Total | 8 | 100.0 |
*BMI, body mass index; TB, tuberculosis; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; EMB, ethambutol; RIF, rifampin.
†Actemra used, 140 days.