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. 2016 Jun 21;113(27):7527–7532. doi: 10.1073/pnas.1604790113

Fig. 3.

Fig. 3.

Interactions of EVN and AVI with H89 and H91 of the 23S rRNA. (A and B) Binding site of EVN (gold) (A) and AVI (red) (B), with nucleotides in H89 and H91 protected from DMS modification highlighted in red and orange, respectively. (C and D) Binding site of EVN (gold) (C) and AVI (red) (D), with resistance mutations in H89 and H91 highlighted in blue and green, respectively. (E and F) Secondary structure of 23S rRNA with zoom on H89 (E) and H91 (F), with nucleotides protected by EVN (red) and AVI (orange), EVN (blue) and AVI (green) resistance mutations and methylations (blue star) as indicated (10–18).