Table S1.
Genes with opposite regulated directions in Shhcre;Rfwd2 and Shhcre;Etv4;5 mutants
| Gene symbol | FPKM of RNA-sequencing | Microarray read | Putative ETV binding sites | ||
| Control | Shhcre;Rfwd2 | Control | Shhcre;Etv4;5 | ||
| Cubn | 0.57 | 3.34 | 207.94 | 81.01 | 5′-TCAGGAAGGA-3′; 5′-CAAGGATTCC-3′ |
| Pthlh | 3.52 | 16.82 | 374.81 | 274.37 | 5′-GCAGGAATGC-3′ |
| Lcn2 | 0.57 | 1.90 | 151.17 | 77.71 | 5′-CCAGGATAAT-3′; 5′-GGAGGATGAC-3′ |
| Habp2 | 1.91 | 9.34 | 198.09 | 159.79 | 5′-GGAGGATTGC-3′ |
| Kcnt2 | 0.13 | 0.62 | 88.03 | 67.18 | 5′-TCAGGAAAGT-3′ |
| Slc39a8 | 5.48 | 18.40 | 354.59 | 272.48 | 5′-TCAGGAAGGG-3′; 5′-ACAGGAAAGT-3′; 5′-TGCGGATATC-3′ |
| Cfi | 11.24 | 29.22 | 190.02 | 116.16 | 5′-CCAGGAAGAA-3′; 5′-ACAGGAAGGG-3′; 5′-AAAGGAAAAC-3′ |
| Id2 | 121.83 | 270.55 | 5,673.41 | 4,608.24 | 5′-CGCGGAAGAA-3′ |
| Sftpa1 | 5.20 | 11.40 | 396.18 | 321.80 | 5′-AAAGGATGCC-3′ |
| Pla2g7 | 4.25 | 9.27 | 290.02 | 240.52 | 5′-TCAGGATTGG-3′; 5′-AGAGGATGTT-3′ |
| Rxfp1 | 0.26 | 0.53 | 70.03 | 56.10 | 5′-AGAGGAAAGA-3′; 5′-AAAGGAAGGG-3′; 5′-AAAGGATTTT-3′ |
| Tmem100 | 7.39 | 14.59 | 333.14 | 247.28 | 5′-TCCGGAATTC-3′; 5′-TAAGGAAGAG-3′ |
| Sh3bgrl2 | 6.66 | 12.79 | 975.50 | 588.13 | 5′-CCAGGAAAAA-3′; 5′-AGAGGATGCT-3′; 5′-CAAGGAAACT-3′ |
| Slc26a9 | 1.08 | 1.89 | 335.46 | 209.38 | 5′-AGAGGAATCT-3′ |
| Map2 | 3.73 | 6.08 | 552.56 | 451.94 | 5′-GAAGGAAGGA-3′; 5′-AAAGGATTCA-3′ |
| Rcsd1 | 15.45 | 24.77 | 288.01 | 219.79 | 5′-GGAGGATAAC-3′; 5′-TCAGGATTGC-3′ |
| Otud1 | 5.08 | 8.08 | 294.07 | 243.88 | 5′-TCCGGAAGTG-3′; 5′-GGAGGAAACG-3′; 5′-CAAGGAAGGC-3′ |
| Slc2a3 | 5.32 | 7.88 | 377.41 | 284.05 | 5′-GGAGGATGGC-3′; 5′-AACGGAAAGC-3′ |
| Il1r1 | 2.19 | 3.12 | 265.03 | 218.27 | 5′-GCAGGAATAA-3′; 5′-GCAGGATTAA-3′ |
| Bex4 | 85.78 | 116.82 | 191.34 | 119.43 | 5′-GGCGGAAAGA-3′; 5′-GAAGGAAAAA-3′; 5′-TCAGGAAGTT-3′ |
| Npr3 | 11.73 | 15.81 | 1,964.57 | 1,468.37 | 5′-AGAGGAAAGA-3′; 5′-GGAGGAAAAG-3′; 5′-AGAGGAATCT-3′ |
| Afap1l1 | 37.03 | 48.04 | 781.44 | 600.49 | 5′-TCAGGAAAGA-3′; 5′-GGAGGAATGC-3′ |
| Tgfbr3 | 5.69 | 7.25 | 704.28 | 451.94 | 5′-CCAGGAATCC-3′; 5′-AAAGGAATTT-3′ |
| Pde4b | 6.03 | 7.64 | 364.56 | 300.25 | 5′-TGAGGAAACC-3′; 5′-AGAGGATTCA-3′ |
| Plb1 | 2.02 | 0.43 | 218.27 | 286.03 | 5′-ACAGGAATAA-3′; 5′-TCAGGATATG-3′; 5′-CCAGGATTGC-3′; 5′-TGCGGAAAAC-3′; 5′-TGAGGAAATA-3′; 5′-GAAGGAAAGA-3′ |
| Gal | 6.29 | 1.88 | 206.50 | 304.44 | 5′-GAAGGAAAGC-3′ |
| Cldn10 | 9.51 | 3.61 | 643.59 | 803.41 | 5′-ACAGGAAATT-3′ |
| Entpd3 | 9.25 | 3.96 | 744.43 | 916.51 | 5′-ACAGGATGTG-3′; 5′-AAAGGATTGG-3′ |
| Ankrd33b | 0.80 | 0.39 | 99.04 | 122.79 | 5′-GGCGGATTAC-3′ |
| Ces1d | 13.50 | 6.64 | 377.41 | 471.14 | 5′-GCAGGAATAC-3′; 5′-GAAGGAAGAG-3′; 5′-CAAGGATTGT-3′; 5′-CCAGGAAGGC-3′ |
| Slc27a6 | 13.15 | 7.34 | 445.72 | 576.03 | 5′-ACAGGAAACC-3′; 5′-GGAGGAAGAT-3′ |
| Tinag | 7.49 | 4.89 | 709.18 | 910.17 | 5′-AGAGGATTCT-3′ |
| Gsta4 | 63.55 | 44.47 | 955.43 | 1,478.58 | 5′-ACAGGAATCG-3′ |
| Aldh1a7 | 52.35 | 36.73 | 1,389.16 | 1,833.01 | 5′-ACAGGAAATA-3′ |
| Fam89a | 12.36 | 9.09 | 274.37 | 333.14 | 5′-GACGGAAGAC-3′ |
| Ano1 | 11.04 | 7.85 | 803.41 | 1,038.29 | — |
| Aard | 8.63 | 11.29 | 164.28 | 129.79 | — |
| Sox9 | 11.44 | 14.21 | 1,833.01 | 1,478.58 | — |
| Scgb3a2 | 14.25 | 1.83 | 66.72 | 81.01 | — |
| Ascl1 | 1.87 | 1.08 | 526.39 | 694.58 | — |
| Igfbp6 | 4.28 | 2.51 | 97.01 | 120.26 | — |
| Nptx1 | 0.44 | 0.11 | 114.56 | 144.01 | — |
| Ndp | 2.71 | 4.07 | 245.57 | 162.02 | — |
| Gfra1 | 4.72 | 2.78 | 430.54 | 526.39 | — |
| Dram1 | 11.44 | 24.36 | 699.41 | 552.56 | — |
FPKM, fragments per kilobase of exon every million reads mapped.