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. 2016 Jun 16;113(27):E3950–E3959. doi: 10.1073/pnas.1601747113

Table S2.

Pharmacology of dual-tagged GluA2-CFP/YFP receptors

l-glutamate CTZ DNQX
Receptor EC50, μM EC50, μM IC50, nM
WT GluA2 28 [27–31] 6 [5–9] 1154 [857–1552]
GluA2-0Y-6C 81 [66–100] 11 [8–15] 562 [391–809]
GluA2-0Y-10C 30 [27–33] 9 [6–13] 845 [308–2598]
GluA2-3Y-6C 108 [99–117]* 7 [5–10] 156 [90–271]*
GluA2-3Y-10C 25 [22–29] 9 [7–11] 444 [234–843]
GluA2-6Y-10C 46 [41–50] 12 [10–15] 163 [50–535]*
*

P < 0.05 value statistically significantly different from WT GluA2.

Data represent EC50 or IC50 obtained from fitting of composite dose–response data (Fig. S1) from experiments at five to nine oocytes (95% confidence intervals in brackets).