Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jul 11;6:29431. doi: 10.1038/srep29431

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A) Interaction mode of BmP02 with Kv1.3 channel. BmP02 key functional residues are marked. (B) Kv1.3 channel pore-blocking Lys11 of Bmp02 primarily contacts the conserved residues of Kv1.3 channel pore region within a contact distance of 5 nm. (C) His9 of BmP02 interacts with Ser426 and His451 in channel D chain within a contact distance of 5 nm. (D) Lys13 of BmP02 mainly contacted channel Asp449 in B chian, Gly450 and Met 452 in A chain within a contact distance of 5 nm. (E) The RSMF value of all BmP02 residues during the MD simulation. (F) Mean values of Virtual Alanine Mutation of Kv1.3-BmP02 complex obtained from ZDOCK and MD simulations with standard deviation.