Table 1. The bonds forming by the three Key residues to Kv1.3 channel vestibule.
| Ligand residues | Receptor residue | Bond type | Distance (Å) |
|---|---|---|---|
| HIS9 | D:HIS451 | Hydrogen bond | 2.0377 |
| HIS9 | D:SER426 | Hydrogen bond | 1.8243 |
| LYS11 | D:ASP449 | Hydrogen bond | 2.1291 |
| LYS11 | A:TYR447 | Hydrogen bond | 1.7427 |
| LYS11 | B:TYR447 | Hydrogen bond | 1.7719 |
| LYS11 | A:GLY448 | Hydrogen bond | 1.6409 |
| LYS11 | C:GLY448 | Hydrogen bond | 1.5288 |
| LYS11 | D:TYR447 | Hydrogen bond | 1.9719 |
| LYS11 | A:HIS451 | Hydrogen bond | 2.6921 |
| LYS11 | B:GLY450 | Hydrogen bond | 3.0127 |
| LYS11 | B:TYR447 | Hydrogen bond | 2.4364 |
| LYS13 | B:GLY450 | Hydrogen bond | 1.8004 |
| LYS13 | B:MET452 | Hydrogen bond | 1.5996 |
| LYS13 | B:GLY450 | Hydrogen bond | 2.6768 |
| LYS13 | A:ASP449 | Salt bridge | 2.2948 |
The distance of the contact was less than 5 Å.