Table 3.
Comparison of deduced amino acid of the HA1 region between the Vietnamese SIVs and human seasonal influenza viruses isolated in 2004 and 2005
| Designation of antigenic site* | Amino acid changes position at** | |||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3 | 10 | 25 | 53 | 62 | 111 | 122 | 124 | 133 | 135 | 138 | 142 | 144 | 145 | 156 | 158 | 159 | 165 | 186 | 188 | 193 | 201 | 209 | 219 | 225 | 253 | 261 | 264 | |
| – | C | – | A | – | A | B | – | A | D | – | ||||||||||||||||||
| A/swine/Binh Duong/03_06/2010 | F | M*** | M | N | G | I | S*** | N | N | K*** | S | G | D*** | S | H | N | N | K*** | G | Y | S | I | N | S | D | A | Q | R |
| A/swine/Binh Duong/03_08/2010 | P | |||||||||||||||||||||||||||
| A/swine/Binh Duong/03_09/2010 | ||||||||||||||||||||||||||||
| A/swine/Binh Duong/03_10/2010 | ||||||||||||||||||||||||||||
| A/swine/Binh Duong/03_13/2010 | K | |||||||||||||||||||||||||||
| A/swine/Binh Duong/03_14/2010 | R | |||||||||||||||||||||||||||
| A/New York/55/2004 | L | T | I | D | E | L | N | S | T | R | N | N | K | F | N | V | D | R | R | S | Y | R | K | |||||
| A/Hiroshima/52/2005 | L | T | I | D | E | L | N | S | T | A | R | N | N | R | K | F | N | D | F | R | S | N | R | K | ||||
SIV, swine influenza viruse.
*Designation to the predicted antigenic sites of the H3 HA 8 was shown. –, indicates no designation to the corresponding amino acid.
**Only locations where differences were observed are indicated.
***Substitution at the amino acid results in loss of glycosylation on the HA molecules of the Vietnamese isolates.