Table 1. The developed device can apply 25 separate mechanical stimulation conditions to cells.

Condition number	Strain condition number	Trench shape	Trench dimensions	Orientation angle of trench major axis with respect to flow
1	1	circular	radius 1.25 mm	–
2	2	circular	radius 1.5 mm	–
3	3	circular	radius 1.75 mm	–
4	4	circular	radius 2 mm	–
5	5	circular	radius 2.5 mm	–
6	6	ellipse	half minor axis 1.55 mm half major axis 2.3 mm	0°
7				30°
8				45°
9				60°
10				90°
11	7	ellipse	half minor axis 1.7 mm half major axis 2.3 mm	0°
12				30°
13				45°
14				60°
15				90°
16	8	ellipse	half minor axis 1.9 mm half major axis 2.3 mm	0°
17				30°
18				45°
19				60°
20				90°
21	9	ellipse	half minor axis 2.1 mm half major axis 2.3 mm	0°
22				30°
23				45°
24				60°
25				90°

The conditions are listed here and assigned a condition number each for ease of identification. In the absence of flow, the variously oriented strain conditions are identical and hence a strain condition number is also defined to collectively refer to these identical strain conditions.